Imperial College London and Spain University of Vigo Scientist developed a ultra-sensitive bio-sensor which are able to detect diseases in earliest stages. Scientist claims that their bio-sensor test can detect bio-markers at concentration level.
The new biosensor consists of nanoscopic-sized gold stars suspended in a solution containing blood-derived proteins. Antibodies, which latch onto a biomarker when it is detected in a sample, are attached to the surface of the nanostars. In their study, the researchers used an antibody that latches onto Prostate Specific Antigen (PSA), a biomarker associated with prostate cancer. A secondary antibody, which has an enzyme called glucose oxidase attached to it, creates a distinctive silver crystal coating on the gold stars that can be detected through an optical microscope, thus signaling that PSA is present.
The researchers next plan to conduct further clinical testing to examine the potential of the new biomarker in detecting different biomarkers associated with HIV and other infections.
The new biosensor consists of nanoscopic-sized gold stars suspended in a solution containing blood-derived proteins. Antibodies, which latch onto a biomarker when it is detected in a sample, are attached to the surface of the nanostars. In their study, the researchers used an antibody that latches onto Prostate Specific Antigen (PSA), a biomarker associated with prostate cancer. A secondary antibody, which has an enzyme called glucose oxidase attached to it, creates a distinctive silver crystal coating on the gold stars that can be detected through an optical microscope, thus signaling that PSA is present.
The researchers next plan to conduct further clinical testing to examine the potential of the new biomarker in detecting different biomarkers associated with HIV and other infections.
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